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Peptide record

TPDB02494

Antibacterial Anticancer Hemolysis Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02494
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KLLLKFKKLQ
Physicochemical Analysis
C62H111N15O12
ARNDCEGHIMPSTWYV
LK
1258.66
11.00
4
0
5
+4
1.17
-0.110
156.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
4
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C62H111N15O12
1258.66
11.00
+4
1.17
-0.110
Evidence Records 4 records
Evidence 1 Activity

Activity

IC50
Hemolysis
89
Human erythrocytes: 89 ± 5.3% Hemolysis=375 µM IC50=89 ± 5.3 µM

Target

Human erythrocytes

Source & Reference

Hemolytik PD_Hemolysis
DRAMP4
Peptides. 2010 Nov 31(11):2017-26

Other

Source Activity Label Source Definition
Hemolysis
Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

89% Hemolysis
Toxicity
375 µM
Hemolytic Cytotoxic
89% Hemolysis | 375 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 3 Activity

Activity

IC50
Toxicity
89
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 89 ± 5.3% Hemolysis=375 µM IC50=89 ± 5.3 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2010 Nov 31(11):2017-26
Evidence 4 Hemolysis

Activity

89
IC50
Human erythrocytes: 89 ± 5.3% Hemolysis=375 µM IC50=89 ± 5.3 µM
Hemolysis

Target

Human erythrocytes

Source & Reference

HemoPI PD_Hemolysis
Peptides. 2010 Nov 31(11):2017-26
DRAMP4
PD_Hemolysis