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Peptide record

TPDB02484

Antibacterial Hemolysis Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB02484
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
KFFKFFKFF
Physicochemical Analysis
C72H92N12O10
ARNDCEQGHILMPSTWYV
F
1285.60
10.84
3
0
6
+3
-3.81
0.567
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
6
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 6 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C72H92N12O10
1285.60
10.84
+3
-3.81
0.567
Evidence Records 2 records
Evidence 1 Activity

Activity

>5% Hemolysis
Toxicity
40 µg/mL
Hemolytic Cytotoxic
>5% Hemolysis | 40 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Group of peptides that act synergistically with hydrophobic antibiotics against gram-negative enteric bacteria. | Antimicrob Agents Chemother | 1996
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis