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Peptide record

TPDB02457

Antibacterial Hemolysis Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB02457
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
FWRRFWRR
Physicochemical Analysis
C64H88N22O9
ANDCEQGHILKMPSTYV
R
1309.54
12.88
4
0
4
+4
-2.72
-1.775
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
839.99
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
8
C64H88N22O9
1309.54
12.88
+4
-2.72
-1.775
Evidence Records 11 records
Evidence 1 Activity

Activity

18±6.7 Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
18±6.7 Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 2 Activity

Activity

45.1±20.5 Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
45.1±20.5 Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 3 Activity

Activity

11.6±3.2 Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
11.6±3.2 Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 4 Activity

Activity

26.3±12.3 Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
26.3±12.3 Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 5 Activity

Activity

18.3±12.8 Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
18.3±12.8 Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 6 Activity

Activity

41.9±19.9% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
41.9±19.9% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 7 Activity

Activity

10±2.2 Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
10±2.2 Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 8 Activity

Activity

14.6±3.2 Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
14.6±3.2 Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 9 Activity

Activity

13±0.7 Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
13±0.7 Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 10 Activity

Activity

15.9±2.6 Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
15.9±2.6 Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application. | Int J Mol Sci | 2019
Evidence 11 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis