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Peptide record

TPDB02439

Antibacterial Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB02439
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 8-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FWRIRIRR
Physicochemical Analysis
C56H91N21O9
ANDCEQGHLKMPSTYV
R
1202.47
12.88
4
0
4
+4
-0.36
-0.887
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
457.39
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
8
C56H91N21O9
1202.47
12.88
+4
-0.36
-0.887
Evidence Records 3 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides. | J Biol Chem | 2011
Evidence 2 Activity

Activity

17% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
17% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides. | J Biol Chem | 2011
Evidence 3 Activity

Activity

12% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
12% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides. | J Biol Chem | 2011