Back to search

Peptide record

TPDB02431

Antibacterial Antifungal Antiparasitic Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB02431
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FDIMGLIKKVAGAL
Physicochemical Analysis
C69H118N16O17S1
RNCEQHPSTWY
AGILK
1475.85
9.88
2
1
9
+1
-0.14
1.214
146.43
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
2
I
2
L
2
K
1
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 2 M: 1 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
14
C69H118N16O17S1
1475.85
9.88
+1
-0.14
1.214
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Active against
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
50% Hemolysis | 200 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Chemical and biological characterization of four new linear cationic a-helical peptides from the venoms of two solitary eumenine wasps. | Toxicon | 2011
Evidence 5 Activity

Activity

EC50
Toxicity
200 µM
Hemolytic
Hemolytic_activity: [Ref.21549739]EC50=200 µM against mice erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Toxicon. 2011 Jun 57(7-8):1081-1092.