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Peptide record

TPDB02421

Antibacterial Anticancer Antifungal Antiparasitic standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB02421
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb i2APP
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFLSTVKNLATNVAGTVIDTLKCKVTGGCRS
Physicochemical Analysis
C135H233N39O43S2
EQHMPWY
T
3154.69
9.80
4
1
11
+3
3.19
0.345
94.19
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.96
11
Residue Composition
number
2
A
1
R
2
N
1
D
2
C
0
E
0
Q
4
G
0
H
1
I
3
L
3
K
0
M
1
F
0
P
2
S
5
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 1 C: 2 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 3 K: 3 M: 0 F: 1 P: 0 S: 2 T: 5 W: 0 Y: 0 V: 4
Chemical Descriptors
31
C135H233N39O43S2
3154.69
9.80
+3
3.19
0.345
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
120 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Very weakly active against E. coli (MIC 120 uM) but not S.aureus (MIC >150 uM) and C.albicans (MIC >150 uM). Provided by Erik Martin. Upd
Evidence 2 Activity

Activity

MIC
Antibacterial
>150 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP

Other

Very weakly active against E. coli (MIC 120 uM) but not S.aureus (MIC >150 uM) and C.albicans (MIC >150 uM). Provided by Erik Martin. Updated 7/2021 12/2023
Evidence 3 Activity

Activity

MIC
Antibacterial
>150 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP

Other

Very weakly active against E. coli (MIC 120 uM) but not S.aureus (MIC >150 uM) and C.albicans (MIC >150 uM). Provided by Erik Martin. Updated 7/2021 12/2023
Evidence 4 Activity

Activity

MIC
Antifungal
120 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Very weakly active against E. coli (MIC 120 uM) but not S.aureus (MIC >150 uM) and C.albicans (MIC >150 uM). Provided by Erik Martin. Upd
Evidence 5 Activity

Activity

MIC
Antifungal
>150 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Very weakly active against E. coli (MIC 120 uM) but not S.aureus (MIC >150 uM) and C.albicans (MIC >150 uM). Provided by Erik Martin. Updated 7/2021 12/2023
Evidence 6 Activity

Activity

MIC
Antifungal
>150 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Very weakly active against E. coli (MIC 120 uM) but not S.aureus (MIC >150 uM) and C.albicans (MIC >150 uM). Provided by Erik Martin. Updated 7/2021 12/2023
Evidence 7 Activity

Activity

MIC
Antiparasitic
120 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Very weakly active against E. coli (MIC 120 uM) but not S.aureus (MIC >150 uM) and C.albicans (MIC >150 uM). Provided by Erik Martin. Upd
Evidence 8 Activity

Activity

MIC
Antiparasitic
>150 µM

Target

S.aureus

Source & Reference

DRAMP

Other

Very weakly active against E. coli (MIC 120 uM) but not S.aureus (MIC >150 uM) and C.albicans (MIC >150 uM). Provided by Erik Martin. Updated 7/2021 12/2023
Evidence 9 Activity

Activity

MIC
Antiparasitic
>150 µM

Target

C.albicans

Source & Reference

DRAMP

Other

Very weakly active against E. coli (MIC 120 uM) but not S.aureus (MIC >150 uM) and C.albicans (MIC >150 uM). Provided by Erik Martin. Updated 7/2021 12/2023