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Peptide record

TPDB02420

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB02420
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLNTLKKVFQGLHEAIKLINNHVQ
Physicochemical Analysis
C123H204N36O33
RDCMPSWY
L
2715.19
10.32
5
1
10
+2
5.47
-0.142
125.83
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
6
Residue Composition
number
1
A
0
R
3
N
0
D
0
C
1
E
2
Q
2
G
2
H
2
I
4
L
3
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 3 D: 0 C: 0 E: 1 Q: 2 G: 2 H: 2 I: 2 L: 4 K: 3 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C123H204N36O33
2715.19
10.32
+2
5.47
-0.142
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 4.5 uM). Warning: other bacteria not tested. Virus: inhibited Human Immunodeficiency Virus Type 1
Evidence 2 Activity

Activity

MIC
Antifungal
4.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 4.5 uM). Warning: other bacteria not tested. Virus: inhibited Human Immunodeficiency Virus Type 1
Evidence 3 Activity

Activity

MIC
Antiparasitic
4.5 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against E. coli (MIC 4.5 uM). Warning: other bacteria not tested. Virus: inhibited Human Immunodeficiency Virus Type 1
Evidence 4 Activity

Activity

MIC
Antiviral
4.5 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against E. coli (MIC 4.5 uM). Warning: other bacteria not tested. Virus: inhibited Human Immunodeficiency Virus Type 1
Evidence 5 Activity

Activity

50% Cell death
Toxicity
>36.8 µM
Cytotoxic
50% Cell death | >36.8 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010