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Peptide record

TPDB02400

Antibacterial Anticancer Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB02400
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RRLFRRILRRL
Physicochemical Analysis
C69H127N29O12
ANDCEQGHKMPSTWYV
R
1554.95
13.10
6
0
5
+6
1.74
-0.755
141.82
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C69H127N29O12
1554.95
13.10
+6
1.74
-0.755
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
Toxicity
68.0±7.6 µM
Cytotoxic
IC50 | 68.0±7.6 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties. | Org Biomol Chem | 2014
Evidence 2 Activity

Activity

(1±0.1)% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
(1±0.1)% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties. | Org Biomol Chem | 2014
Evidence 3 Activity

Activity

IC50
Toxicity
68.0
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 1±0.1% Hemolysis=150µM | Cytotoxicity: NIH 3T3: IC50=68.0±7.6µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Org Biomol Chem. 2014 Mar 14 12(10):1652-63.