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Peptide record

TPDB02392

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB02392
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb iACP-DRLF pep-lab Antifp Antifungipept CAFPdb dbAMP AI4AVP dbAMP 3.0 DRAVP 2.0 PD_Hemolysis ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
FAKKFAKKFKKFAKKFAKFAFAF
Physicochemical Analysis
C144H212N32O24
RNDCEQGHILMPSTWYV
K
2775.47
11.41
9
0
14
+9
-1.15
-0.083
26.09
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
9
K
0
M
8
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 9 M: 0 F: 8 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C144H212N32O24
2775.47
11.41
+9
-1.15
-0.083
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
52 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 52 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Periodic antimicrobial peptides. | PATENT US 7091185 B2 | 2006
Evidence 2 Activity

Activity

93.1% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
93.1% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Periodic antimicrobial peptides. | PATENT US 7091185 B2 | 2006
Evidence 3 Activity

Activity

50% Cytotoxicity
Toxicity
3.43 µM
Cytotoxic
50% Cytotoxicity | 3.43 | µM | target cell: Feline kidney epithelial CRFK cells

Target

Feline kidney epithelial CRFK cells

Source & Reference

NA
DBAASP
Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro. | J Virol | 2002
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis