Back to search

Peptide record

TPDB02388

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB02388
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RAGLKFPVGRVHRLLR
Physicochemical Analysis
C85H147N31O17
NDCEQIMSTWY
R
1875.30
12.88
6
0
7
+5
2.82
-0.194
115.62
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
3
L
1
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 3 K: 1 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
16
C85H147N31O17
1875.30
12.88
+5
2.82
-0.194
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9.6 µM

Target

Escherichia coli HP101BA 7601c

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli HP101BA 7601c (MIC 9.6 uM), K. pneumonia PTCC1388 (MIC 10.6 uM), M. luteus PTCC1625 (MIC 6.0 uM), and S. aureus PTCC
Evidence 2 Activity

Activity

MIC
Antibacterial
10.6 µM

Target

K. pneumonia PTCC1388

Source & Reference

dbAMP DRAMP

Other

Active against E. coli HP101BA 7601c (MIC 9.6 uM), K. pneumonia PTCC1388 (MIC 10.6 uM), M. luteus PTCC1625 (MIC 6.0 uM), and S. aureus PTCC1431 (MIC 8.1 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
6.0 µM

Target

M. luteus PTCC1625

Source & Reference

dbAMP DRAMP

Other

Active against E. coli HP101BA 7601c (MIC 9.6 uM), K. pneumonia PTCC1388 (MIC 10.6 uM), M. luteus PTCC1625 (MIC 6.0 uM), and S. aureus PTCC1431 (MIC 8.1 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
8.1 µM

Target

Staphylococcus aureus PTCC1431

Source & Reference

dbAMP DRAMP

Other

c (MIC 9.6 uM), K. pneumonia PTCC1388 (MIC 10.6 uM), M. luteus PTCC1625 (MIC 6.0 uM), and S. aureus PTCC1431 (MIC 8.1 uM).
Evidence 5 Activity

Activity

3% Hemolysis
Toxicity
60 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 60 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel antibacterial peptides from skin secretions of Euphlyctis cyanophlyctis. | Int J Pept Res Ther | 2012
Evidence 6 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.Int J Pept Res Ther(2012)18 107.]<3% hemolytic activity at 60 µg/ml against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Int. J. Pept. Res. Ther. 2012 18:107-115.