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Peptide record

TPDB02387

Antibacterial Anticancer Antifungal Antiparasitic standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB02387
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPILASLAATLGPKLLCLITKKC
Physicochemical Analysis
C119H207N27O28S2
RNDEQHMWYV
L
2528.24
9.80
3
0
13
+3
-2.37
1.304
158.75
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.94
5
Residue Composition
number
3
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
2
I
7
L
3
K
0
M
1
F
2
P
1
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 7 K: 3 M: 0 F: 1 P: 2 S: 1 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C119H207N27O28S2
2528.24
9.80
+3
-2.37
1.304
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
35 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against C. albicans (MIC 35 uM), E.coli (MIC>50 uM), and S. aureus (MIC 8 uM). Also active against B. dendrobatidis (Tabl
Evidence 2 Activity

Activity

MIC
Antibacterial
>50 µM

Target

E.coli

Source & Reference

dbAMP DRAMP

Other

Active against C. albicans (MIC 35 uM), E.coli (MIC>50 uM), and S. aureus (MIC 8 uM). Also active against B. dendrobatidis (Table 1, Rollins-Smith,
Evidence 3 Activity

Activity

MIC
Antibacterial
8 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against C. albicans (MIC 35 uM), E.coli (MIC>50 uM), and S. aureus (MIC 8 uM). Also active against B. dendrobatidis (Table 1, Rollins-Smith, BBA 2009 1788:1593-1599).
Evidence 4 Activity

Activity

MIC
Antifungal
35 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against C. albicans (MIC 35 uM), E.coli (MIC>50 uM), and S. aureus (MIC 8 uM). Also active against B. dendrobatidis (Tabl
Evidence 5 Activity

Activity

MIC
Antifungal
>50 µM

Target

E.coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against C. albicans (MIC 35 uM), E.coli (MIC>50 uM), and S. aureus (MIC 8 uM). Also active against B. dendrobatidis (Table 1, Rollins-Smith,
Evidence 6 Activity

Activity

MIC
Antifungal
8 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against C. albicans (MIC 35 uM), E.coli (MIC>50 uM), and S. aureus (MIC 8 uM). Also active against B. dendrobatidis (Table 1, Rollins-Smith, BBA 2009 1788:1593-1599).
Evidence 7 Activity

Activity

MIC
Antiparasitic
35 µM

Target

Candida albicans

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against C. albicans (MIC 35 uM), E.coli (MIC>50 uM), and S. aureus (MIC 8 uM). Also active against B. dendrobatidis (Tabl
Evidence 8 Activity

Activity

MIC
Antiparasitic
>50 µM

Target

E.coli

Source & Reference

DRAMP

Other

Active against C. albicans (MIC 35 uM), E.coli (MIC>50 uM), and S. aureus (MIC 8 uM). Also active against B. dendrobatidis (Table 1, Rollins-Smith,
Evidence 9 Activity

Activity

MIC
Antiparasitic
8 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Active against C. albicans (MIC 35 uM), E.coli (MIC>50 uM), and S. aureus (MIC 8 uM). Also active against B. dendrobatidis (Table 1, Rollins-Smith, BBA 2009 1788:1593-1599).