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Peptide record

TPDB02371

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB02371
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GVGDLIRKAVSVIKNIV
Physicochemical Analysis
C80H145N23O22
CEQHMFPTWY
V
1781.17
10.59
3
1
9
+2
3.21
0.882
165.88
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
1
R
1
N
1
D
0
C
0
E
0
Q
2
G
0
H
3
I
1
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 1 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
17
C80H145N23O22
1781.17
10.59
+2
3.21
0.882
Evidence Records 30 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

B. cereus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureu
Evidence 2 Activity

Activity

MIC
Antibacterial
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP DRAMP

Other

Active against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epid
Evidence 3 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

L. innocua

Source & Reference

dbAMP DRAMP

Other

Active against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S
Evidence 4 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

ive against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E
Evidence 5 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

5 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), an
Evidence 6 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP

Other

ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) (
Evidence 7 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

S. uberis

Source & Reference

dbAMP DRAMP

Other

), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al.,
Evidence 8 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al., 2004 ). Also active agai
Evidence 9 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

P. multocida

Source & Reference

dbAMP DRAMP

Other

S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al., 2004 ). Also active against M. luteus (MIC 2-4 uM), less ac
Evidence 10 Activity

Activity

MIC
Antibacterial
2-4 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

d P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al., 2004 ). Also active against M. luteus (MIC 2-4 uM), less active against S. hominis, S. epidermidis, and S. aureus (disc diffusion assay).
Evidence 11 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

B. cereus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureu
Evidence 12 Activity

Activity

MIC
Antifungal
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epid
Evidence 13 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

L. innocua

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S
Evidence 14 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

M. luteus

Source & Reference

dbAMP DRAMP Antifungipept

Other

ive against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E
Evidence 15 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

5 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), an
Evidence 16 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP Antifungipept

Other

ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) (
Evidence 17 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

S. uberis

Source & Reference

dbAMP DRAMP Antifungipept

Other

), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al.,
Evidence 18 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al., 2004 ). Also active agai
Evidence 19 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

P. multocida

Source & Reference

dbAMP DRAMP Antifungipept

Other

S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al., 2004 ). Also active against M. luteus (MIC 2-4 uM), less ac
Evidence 20 Activity

Activity

MIC
Antifungal
2-4 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP Antifungipept

Other

d P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al., 2004 ). Also active against M. luteus (MIC 2-4 uM), less active against S. hominis, S. epidermidis, and S. aureus (disc diffusion assay).
Evidence 21 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

B. cereus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureu
Evidence 22 Activity

Activity

MIC
Antiparasitic
3 µg/mL

Target

L. lactis

Source & Reference

DRAMP

Other

Active against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epid
Evidence 23 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

L. innocua

Source & Reference

DRAMP

Other

Active against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S
Evidence 24 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

M. luteus

Source & Reference

DRAMP

Other

ive against B. cereus (MIC 25 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E
Evidence 25 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

5 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), an
Evidence 26 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

DRAMP

Other

ug/ml), L. innocua (MIC 25 ug/ml), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) (
Evidence 27 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

S. uberis

Source & Reference

DRAMP

Other

), M. luteus (MIC 12.5 ug/ml), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al.,
Evidence 28 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

), S. aureus (MIC 50 ug/ml), S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al., 2004 ). Also active agai
Evidence 29 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

P. multocida

Source & Reference

DRAMP

Other

S. epidermidis (MIC 12.5 ug/ml), S. uberis (MIC 12.5 ug/ml), E. coli (MIC>100 ug/ml), and P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al., 2004 ). Also active against M. luteus (MIC 2-4 uM), less ac
Evidence 30 Activity

Activity

MIC
Antiparasitic
2-4 µM

Target

M. luteus

Source & Reference

DRAMP

Other

d P. multocida (MIC >100 ug/ml) ( reviewed by Apponyi et al., 2004 ). Also active against M. luteus (MIC 2-4 uM), less active against S. hominis, S. epidermidis, and S. aureus (disc diffusion assay).