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Peptide record

TPDB02357

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB02357
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb AI4AVP AVPpred-BWR dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLFGVLAKVAAHVVPAIAEHF
Physicochemical Analysis
C103H160N26O24
RNDCQMSTWY
A
2146.56
7.97
3
1
14
+0
1.14
1.300
134.76
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
1
E
0
Q
2
G
2
H
1
I
2
L
1
K
0
M
2
F
1
P
0
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 2 I: 1 L: 2 K: 1 M: 0 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
21
C103H160N26O24
2146.56
7.97
+0
1.14
1.300
Evidence Records 41 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

B. cereus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multoc
Evidence 2 Activity

Activity

MIC
Antibacterial
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP DRAMP

Other

Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. au
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

L. innocua

Source & Reference

dbAMP DRAMP

Other

Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. ub
Evidence 4 Activity

Activity

MIC
Antibacterial
12 µg/mL

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

ty against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epi
Evidence 5 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

P. multocida

Source & Reference

dbAMP DRAMP

Other

50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. f
Evidence 6 Activity

Activity

MIC
Antibacterial
6-12 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

g/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.co
Evidence 7 Activity

Activity

MIC
Antibacterial
3 µg/mL

Target

S. uberis

Source & Reference

dbAMP DRAMP

Other

g/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also
Evidence 8 Activity

Activity

MIC
Antibacterial
12 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP

Other

ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HI
Evidence 9 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

S. faecalis

Source & Reference

dbAMP DRAMP

Other

/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HIV infection with little adve
Evidence 10 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP DRAMP

Other

/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HIV infection with little adverse effect on T cells (J
Evidence 11 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

B. cereus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multoc
Evidence 12 Activity

Activity

MIC
Antifungal
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. au
Evidence 13 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

L. innocua

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. ub
Evidence 14 Activity

Activity

MIC
Antifungal
12 µg/mL

Target

M. luteus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ty against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epi
Evidence 15 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

P. multocida

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. f
Evidence 16 Activity

Activity

MIC
Antifungal
6-12 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.co
Evidence 17 Activity

Activity

MIC
Antifungal
3 µg/mL

Target

S. uberis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also
Evidence 18 Activity

Activity

MIC
Antifungal
12 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HI
Evidence 19 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

S. faecalis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HIV infection with little adve
Evidence 20 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HIV infection with little adverse effect on T cells (J
Evidence 21 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

B. cereus

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multoc
Evidence 22 Activity

Activity

MIC
Antiparasitic
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP 3.0 DRAMP

Other

Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. au
Evidence 23 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

L. innocua

Source & Reference

dbAMP 3.0 DRAMP

Other

Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. ub
Evidence 24 Activity

Activity

MIC
Antiparasitic
12 µg/mL

Target

M. luteus

Source & Reference

dbAMP 3.0 DRAMP

Other

ty against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epi
Evidence 25 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

P. multocida

Source & Reference

dbAMP 3.0 DRAMP

Other

50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. f
Evidence 26 Activity

Activity

MIC
Antiparasitic
6-12 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP 3.0 DRAMP

Other

g/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.co
Evidence 27 Activity

Activity

MIC
Antiparasitic
3 µg/mL

Target

S. uberis

Source & Reference

dbAMP 3.0 DRAMP

Other

g/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also
Evidence 28 Activity

Activity

MIC
Antiparasitic
12 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP 3.0 DRAMP

Other

ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HI
Evidence 29 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

S. faecalis

Source & Reference

dbAMP 3.0 DRAMP

Other

/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HIV infection with little adve
Evidence 30 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP 3.0 DRAMP

Other

/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HIV infection with little adverse effect on T cells (J
Evidence 31 Activity

Activity

MIC
Antiviral
50 µg/mL

Target

B. cereus

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multoc
Evidence 32 Activity

Activity

MIC
Antiviral
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. au
Evidence 33 Activity

Activity

MIC
Antiviral
100 µg/mL

Target

L. innocua

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Activity against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. ub
Evidence 34 Activity

Activity

MIC
Antiviral
12 µg/mL

Target

M. luteus

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

ty against B. cereus (MIC 50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epi
Evidence 35 Activity

Activity

MIC
Antiviral
50 µg/mL

Target

P. multocida

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

50 ug/ml), L. lactis (MIC 3 ug/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. f
Evidence 36 Activity

Activity

MIC
Antiviral
6-12 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

g/ml), L. innocua (MIC 100 ug/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.co
Evidence 37 Activity

Activity

MIC
Antiviral
3 µg/mL

Target

S. uberis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

g/ml), M. luteus (MIC 12 ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also
Evidence 38 Activity

Activity

MIC
Antiviral
12 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

ug/ml), P. multocida (MIC 50 ug/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HI
Evidence 39 Activity

Activity

MIC
Antiviral
25 µg/mL

Target

S. faecalis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

/ml), S. aureus (MIC 6-12 ug/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HIV infection with little adve
Evidence 40 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

/ml), S. uberis (MIC 3 ug/ml), S. epidermidis (MIC 12 ug/ml), S. faecalis (MIC 25 ug/ml), E.coli (MIC >100 ug/ml). Also, this peptide could inhibit HIV infection with little adverse effect on T cells (J
Evidence 41 Activity

Activity

50% Cytotoxicity
Toxicity
76.6 µg/mL
Cytotoxic
50% Cytotoxicity | 76.6 | µg/mL | target cell: Pig kidney epithelial cells PK15

Target

Pig kidney epithelial cells PK15

Source & Reference

NA
DBAASP
Antiviral activity of Piscidin 1 against pseudorabies virus both in vitro and in vivo | Virol J | 2019