Back to search

Peptide record

TPDB02354

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB02354
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
INWKKIKSIIKAAMN
Physicochemical Analysis
C81H140N22O19S1
RDCEQGHLFPTYV
IK
1758.20
11.00
4
0
8
+4
1.27
-0.053
117.33
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
312.82
3
Residue Composition
number
2
A
0
R
2
N
0
D
0
C
0
E
0
Q
0
G
0
H
4
I
0
L
4
K
1
M
0
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 0 K: 4 M: 1 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C81H140N22O19S1
1758.20
11.00
+4
1.27
-0.053
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. mutans, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µM

Target

C. grabrata

Source & Reference

dbAMP DRAMP

Other

Active against S. mutans, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
0.5 µM

Target

C. neoformans

Source & Reference

dbAMP DRAMP

Other

ns, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
50 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. mutans, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
50 µM

Target

C. grabrata

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. mutans, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
0.5 µM

Target

C. neoformans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ns, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM).
Evidence 7 Activity

Activity

MIC
Antiparasitic
50 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. mutans, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM).
Evidence 8 Activity

Activity

MIC
Antiparasitic
50 µM

Target

C. grabrata

Source & Reference

DRAMP

Other

Active against S. mutans, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
0.5 µM

Target

C. neoformans

Source & Reference

DRAMP

Other

ns, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM).
Evidence 10 Activity

Activity

7% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
7% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
MP-V1 from the Venom of Social Wasp Vespula vulgaris Is a de Novo Type of Mastoparan that Displays Superior Antimicrobial Activities. | Molecules | 2016
Evidence 11 Activity

Activity

20% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
20% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
MP-V1 from the Venom of Social Wasp Vespula vulgaris Is a de Novo Type of Mastoparan that Displays Superior Antimicrobial Activities. | Molecules | 2016