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Peptide record

TPDB02337

Antibacterial Anticancer Cell-penetrating Peptides Toxicity Tumor-homing Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB02337
Antibacterial Anticancer Cell-penetrating Peptides Toxicity Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP TumorHoPe2.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CellPPD-MOD, and other sources, with an available 3D structural model.
Sequence
CREKAKKLFKKILKKL
Physicochemical Analysis
C92H168N26O19S1
NDQGHMPSTWYV
K
1974.57
10.91
8
1
6
+7
6.23
-0.769
103.75
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
0
D
1
C
1
E
0
Q
0
G
0
H
1
I
3
L
7
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 7 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C92H168N26O19S1
1974.57
10.91
+7
6.23
-0.769
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
74.5±4.1 µM
Cytotoxic
IC50 | 74.5±4.1 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties. | Org Biomol Chem | 2014
Evidence 2 Activity

Activity

IC50
Toxicity
74.5
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: NIH 3T3: IC50=74.5±4.1µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Org Biomol Chem. 2014 Mar 14 12(10):1652-63.