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Peptide record

TPDB02325

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB02325
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AFP-GFuse Antifungipept CAFPdb i2APP ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLDSIKGMAISAGKGALQNLLKVASCKLDKTC
Physicochemical Analysis
C144H256N40O44S3
REHFPWY
L
3348.04
9.65
5
2
14
+3
3.68
0.361
115.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.73
8
Residue Composition
number
4
A
0
R
1
N
2
D
2
C
0
E
1
Q
4
G
0
H
2
I
6
L
5
K
1
M
0
F
0
P
3
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 2 C: 2 E: 0 Q: 1 G: 4 H: 0 I: 2 L: 6 K: 5 M: 1 F: 0 P: 0 S: 3 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C144H256N40O44S3
3348.04
9.65
+3
3.68
0.361
Evidence Records 2 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structural study of novel antimicrobial peptides, nigrocins, isolated from Rana nigromaculata. | FEBS Lett | 2001
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:11682065]1.1% hemolytic activity at 100µg/ml against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
FEBS Lett. 2001 Oct 19 507(1):95-100.