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Peptide record

TPDB02273

Tyroserleutide Anticancer Antioxidant Selfassembly standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB02273
Tyroserleutide
Anticancer Antioxidant Selfassembly
Cancer-related peptides Functional / health-promoting peptides Self-assembling and biomaterial peptides
AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF AnOxPePred - 1.0 AODB Multi-AOP SAPdb
standard
No
A 3-aa standard natural multi-activity (Anticancer, Antioxidant, and Selfassembly) peptide sequence curated from AntiCP 2.0, CancerPPD 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
YSL
Physicochemical Analysis
C18H27N3O6
ARNDCEQGHIKMFPTWV
LSY
381.43
5.94
0
0
2
-0
-1.37
0.567
130.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
390.64
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
3
C18H27N3O6
381.43
5.94
-0
-1.37
0.567
Free
L
Linear
Free
Antitumor
Synthetic Peptide
Self-Assembly Information 1 records
Record 1 Selfassembly

Source

31211520
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanoparticle nanoparticles
pH: 7.4 solvent: uranium acetate solution concentration: 0.5% (w/v)
Selfassembly; Nanostructure=Nanoparticle; nanoparticles; Trigger=pH: 7.4; solvent: uranium acetate solution; concentration: 0.5% (w/v)
Transmission Electron Microscopy (TEM)
Selfassembly
Evidence Records 10 records
Evidence 1 Activity

Activity

49.4% cytotoxic at 0.1 µg/ml
Anticancer

Target

Skin Cancer
B16-F10
Skin

Assay & Model

MTT/MTS assay
96-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

51.2% cytotoxic at 1 µg/ml
Anticancer

Target

Skin Cancer
B16-F10
Skin

Assay & Model

MTT/MTS assay
96-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 3 Activity

Activity

53.0% cytotoxic at 10 µg/ml
Anticancer

Target

Skin Cancer
B16-F10
Skin

Assay & Model

MTT/MTS assay
96-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 4 Activity

Activity

61.2% cytotoxic at 100 µg/ml
Anticancer

Target

Skin Cancer
B16-F10
Skin

Assay & Model

MTT/MTS assay
96-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 5 Activity

Activity

39.0% cytotoxic at 0.1 µg/ml
Anticancer

Target

Liver Cancer
BEL-7402
Liver

Assay & Model

MTT/MTS assay
96-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 6 Activity

Activity

20.8% cytotoxic at 1 µg/ml
Anticancer

Target

Liver Cancer
BEL-7402
Liver

Assay & Model

MTT/MTS assay
96-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 7 Activity

Activity

33.8% cytotoxic at 10 µg/ml
Anticancer

Target

Liver Cancer
BEL-7402
Liver

Assay & Model

MTT/MTS assay
96-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 8 Activity

Activity

35.6% cytotoxic at 100 µg/ml
Anticancer

Target

Liver Cancer
BEL-7402
Liver

Assay & Model

MTT/MTS assay
96-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 9 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Evidence 10 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanoparticle nanoparticles Trigger=pH: 7.4 solvent: uranium acetate solution concentration: 0.5% (w/v)
Nanoparticle nanoparticles

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

None specified
pH: 7.4 solvent: uranium acetate solution concentration: 0.5% (w/v)
Transmission Electron Microscopy (TEM)
31211520
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Additional Detail Fields 5 fields
pH: 7.4 solvent: uranium acetate solution concentration: 0.5% (w/v)
None specified
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
31211520
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly