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Peptide record

TPDB02221

β-Casomorphin-5 Anticancer Antihypertensive Antioxidant Antiviral Blood-Brain Barrier Neuropeptide standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB02221
β-Casomorphin-5
Anticancer Antihypertensive Antioxidant Antiviral Blood-Brain Barrier Neuropeptide
Anti-infective peptides Cardiometabolic peptides Cancer-related peptides Delivery and barrier-penetrating peptides Neuroactive peptides Functional / health-promoting peptides
AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF AnOxPePred - 1.0 AoXpDb Multi-AOP B3Pred BBPpredict
standard
No
A 5-aa standard natural multi-activity (Anticancer, Antihypertensive, Antioxidant, and other sources) peptide sequence curated from AntiCP 2.0, CancerPPD 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
YPFPG
Physicochemical Analysis
C30H37N5O7
ARNDCEQHILKMSTWV
P
579.65
5.94
0
0
2
-0
-1.16
-0.420
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
257.05
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
1
F
2
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
5
C30H37N5O7
579.65
5.94
-0
-1.16
-0.420
Linear
Similarity
Tyr-Pro-Phe-Pro-Gly
O=C(NC(C(=O)NCC(=O)O)CC(C)C)C1NCCC1
Evidence Records 2 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
22.4 min

Assay & Model

Efflux study ICU
Origin/Source
half life, brain

Source & Reference

NA
B3Pdb

Other

human,bovine
Saturable
Direct iodination
Evidence 2 Activity

Activity

Blood-Brain Barrier
0.031 min-1

Assay & Model

Efflux study ICU
Origin/Source
Brain elemination rate constant

Source & Reference

NA
B3Pdb

Other

human,bovine
Saturable
Direct iodination