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Peptide record

TPDB02197

ACE inhibitor ACE inhibitors Antioxidant standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB02197
ACE inhibitor
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB Multi-AOP
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
YLGY
Physicochemical Analysis
C26H34N4O7
ARNDCEQHIKMFPSTWV
Y
514.58
5.88
0
0
3
-0
-2.43
0.200
97.50
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
2980
579.11
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
4
C26H34N4O7
514.58
5.88
-0
-2.43
0.200
514.5694
514.2419
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
41.86 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
del Mar Contreras M., Sanchez D., Sevilla M. Á., Recio I., Amigo L.
Resistance of casein-derived bioactive peptides to simulated gastrointestinal digestion. International Dairy Journal 32 (2013) 71-78.
2013
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(O)=O InChI=1S/C26H34N4O7/c1-15(2)11-21(30-24(34)20(27)12-16-3-7-18(31)8-4-16)25(35)28-14-23(33)29-22(26(36)37)13-17-5-9-19(32)10-6-17/h3-10,15,20-22,31-32H,11-14,27H2,1-2H3,(H,28,35)(H,29,33)(H,30,34)(H,36,37)/t20-,21-,22-/m0/s1 InChIKey: GYBRLKVNHHENSF-FKBYEOEOSA-N Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9421) the MBPDB database
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
4