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Peptide record

TPDB02164

ACE inhibitor ACE inhibitors Antihypertensive Antioxidant Bitter standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB02164
ACE inhibitor
ACE inhibitors Antihypertensive Antioxidant Bitter
Cardiometabolic peptides Food sensory peptides Functional / health-promoting peptides
Peptipedia AHTPDB AHTpin AODB Tastepeptides-Meta
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, Antioxidant, and other sources) peptide sequence curated from Peptipedia, AHTPDB, AHTpin, and other sources, with an available 3D structural model.
Sequence
YGG
Physicochemical Analysis
C13H17N3O5
ARNDCEQHILKMFPSTWV
G
295.30
5.94
0
0
1
-0
-0.92
-0.700
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
504.58
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
3
C13H17N3O5
295.30
5.94
-0
-0.92
-0.700
295.2905
295.1164
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
1001.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

3
BIOPEP database of bioactive peptides SMILES: c1cc(ccc1C[C@@H](C(=O)NCC(=O)NCC(=O)O)N)O InChI=1S/C13H17N3O5/c14-10(5-8-1-3-9(17)4-2-8)13(21)16-6-11(18)15-7-12(19)20/h1-4,10,17H,5-7,14H2,(H,15,18)(H,16,21)(H,19,20)/t10-/m0/s1 InChIKey: HIINQLBHPIQYHN-JTQLQIEISA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001, Peptide reveals also immunostimulating activity according to the BIOPEP-UWM database of bioactive peptides (ID 3741) the EROP-Moscow database Inhibitor of citruline uptake in yeasts according to the ChEMBL database the PubChem database Bitter peptide according to BIOPEP database of sensory peptides and amino acids.
Evidence 2 Activity

Activity

IC50
Antihypertensive
1001.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
3
BIOPEP database of bioactive peptides SMILES: c1cc(ccc1C[C@@H](C(=O)NCC(=O)NCC(=O)O)N)O InChI=1S/C13H17N3O5/c14-10(5-8-1-3-9(17)4-2-8)13(21)16-6-11(18)15-7-12(19)20/h1-4,10,17H,5-7,14H2,(H,15,18)(H,16,21)(H,19,20)/t10-/m0/s1 InChIKey: HIINQLBHPIQYHN-JTQLQIEISA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001, Peptide reveals also immunostimulating activity according to the BIOPEP-UWM database of bioactive peptides (ID 3741) the EROP-Moscow database Inhibitor of citruline uptake in yeasts according to the ChEMBL database the PubChem database Bitter peptide according to BIOPEP database of sensory peptides and amino acids.
Evidence 3 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
3