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Peptide record

TPDB02123

ACE inhibitor ACE inhibitors Antibacterial Antioxidant Neuropeptide standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB02123
ACE inhibitor
ACE inhibitors Antibacterial Antioxidant Neuropeptide
Anti-infective peptides Cardiometabolic peptides Neuroactive peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB Multi-AOP
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors, Antibacterial, Antioxidant, and other sources) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
WYT
Physicochemical Analysis
C24H28N4O6
ARNDCEQGHILKMFPSV
TWY
468.51
5.94
0
0
2
-0
-2.65
-0.967
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
6990
1491.97
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
3
C24H28N4O6
468.51
5.94
-0
-2.65
-0.967
468.5012
468.2002
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
54.00 µM
Inhibitor of angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Girgih AT, He R, Aluko RE.
Kinetics and molecular docking studies of the inhibitions of angiotensin converting enzyme and renin activities by hemp seed (Cannabis sativa L.) peptides. J. Agric. Food Chem. 62, 4135−4144, 2014
2014
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H]([C@H](O)C)C(=O)O InChI= 1S/C24H28N4O6/c1-13(29)21(24(33)34)28-23(32)20(10-14-6-8-16(30)9-7-14)27-22(31)18(25)11-15-12-26-19-5-3-2-4-17(15)19/h2-9,12-13,18,20-21,26,29-30H,10-11,25H2,1H3,(H,27,31)(H,28,32)(H,33,34)/t13-,18+,20+,21+/m1/s1 InChIKey: YTHWAWACWGWBLE-MNSWYVGCSA-N Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10016) Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007) 001) according to the BIOPEP-UWM database of bioactive peptides (ID 10017)
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
3