Back to search

Peptide record

TPDB02043

L-Tryptophan Antioxidant Bitter Cell-penetrating Peptides standard
1 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB02043
L-Tryptophan
Antioxidant Bitter Cell-penetrating Peptides
Delivery and barrier-penetrating peptides Food sensory peptides Functional / health-promoting peptides
AODB Tastepeptides-Meta CPPsite3.0
standard
No
A 1-aa standard natural multi-activity (Antioxidant, Bitter, and Cell-penetrating Peptides) peptide sequence curated from AODB, Tastepeptides-Meta, and CPPsite3.0, with an available 3D structural model.
Sequence
W
Physicochemical Analysis
C11H12N2O2
ARNDCEQGHILKMFPSTYV
W
204.23
6.02
0
0
1
-0
-1.85
-0.900
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
2693.06
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
1
C11H12N2O2
204.23
6.02
-0
-1.85
-0.900
Free
L
Hydrophobic
Linear
Free
N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Caco-2 Cell

Assay & Model

Male Sprague Dawley rats weighing 180–220 g and male ddY mice weighing 30–40 g
Male Sprague Dawley rats weighing 180–220 g and male ddY mice weighing 30–40 g

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophobic
Synthetic
Insulin
Intestinal absorption of insulin was significantly enhanced by co-administration with L-tryptophan (16 or 32 mM), comparable to the effect of L-penetratin (0.5 mM).
In vitro and in vivo
C
Additional Detail Fields 1 fields
C