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Peptide record

TPDB01942

ACE inhibitor from jellyfish (Rhopilema esculentum) ACE inhibitors Antihypertensive Antioxidant standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB01942
ACE inhibitor from jellyfish (Rhopilema esculentum)
ACE inhibitors Antihypertensive Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AHTPDB AHTpin AnOxPePred - 1.0 AODB Multi-AOP
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, and Antioxidant) peptide sequence curated from Peptipedia, AHTPDB, AHTpin, and other sources, with an available 3D structural model.
Sequence
VKP
Physicochemical Analysis
C16H30N4O4
ARNDCEQGHILMFSTWY
KPV
342.44
10.10
1
0
1
+1
1.51
-0.433
96.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
3
C16H30N4O4
342.44
10.10
+1
1.51
-0.433
342.4326
342.2260
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
1.30 µM
ACE inhibitor
ah

Source & Reference

NA
Li J., Li Q., Li J., Zhou B.
Peptides derived from Rhopilema esculentum hydrolysate exhibit angiotensin converting enzyme (ACE) inhibitory and antioxidant abilities. Molecules, 19, 13587-13602, doi:10.3390/molecules190913587.
2014
Journal

Other

3
Reveals also antioxidative activity (BIOPEP ID 8434).
Evidence 2 Activity

Activity

IC50
Antihypertensive
1.30 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Li J., Li Q., Li J., Zhou B.
Peptides derived from Rhopilema esculentum hydrolysate exhibit angiotensin converting enzyme (ACE) inhibitory and antioxidant abilities. Molecules, 19, 13587-13602, doi:10.3390/molecules190913587.
2014
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
3
Reveals also antioxidative activity (BIOPEP ID 8434).
Evidence 3 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
3