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Peptide record

TPDB01768

ACE inhibitor from garlic dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) ACE inhibitors Antihypertensive Antioxidant Neuropeptide iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB01768
ACE inhibitor from garlic dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
ACE inhibitors Antihypertensive Antioxidant Neuropeptide iDPPIV
Cardiometabolic peptides Neuroactive peptides Functional / health-promoting peptides
FermFooDB Peptipedia AHTPDB AHTpin AODB Multi-AOP iDPPIV
standard
No
A 2-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, Antioxidant, and other sources) peptide sequence curated from FermFooDB, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
SY
Physicochemical Analysis
C12H16N2O5
ARNDCEQGHILKMFPTWV
SY
268.27
5.94
0
0
1
-0
-0.81
-1.050
0.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1490
555.41
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
2
C12H16N2O5
268.27
5.94
-0
-0.81
-1.050
268.2652
268.1055
Evidence Records 4 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
66.30 µM
ACE inhibitor
ah

Source & Reference

FermFooDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

2
Evidence 2 Activity

Activity

IC50
Antihypertensive
66.30 µM
ACE inhibitor
ah

Source & Reference

AHTPDB FermFooDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
2
Evidence 3 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB FermFooDB
DFBP
Evidence 4 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73
2015
Journal

Other

2
Additional Detail Fields 1 fields
2