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Peptide record

TPDB01653

ACE inhibitor from bovine aphas1-CN (90-93) ACE inhibitors Antioxidant standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB01653
ACE inhibitor from bovine aphas1-CN (90-93)
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB Multi-AOP
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
RYLG
Physicochemical Analysis
C23H37N7O6
ANDCEQHIKMFPSTWV
RGLY
507.59
9.88
1
0
2
+1
-0.68
-0.600
97.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
293.54
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
4
C23H37N7O6
507.59
9.88
+1
-0.68
-0.600
507.5817
507.2797
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
225.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Stuknyte M., Cattaneo S., Masotti F., De Noni I.
Occurrence and fate of ACE-inhibitor peptides in cheeses and in their digestates following in vitro static gastrointestinal digestion. Food Chemistry, 168, 27-33, 2015
2015
Journal

Other

4
BIOPEP-UWM database of bioactive peptides N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)O InChI=1S/C23H37N7O6/c1-13(2)10-17(21(35)28-12-19(32)33)30-22(36)18(11-14-5-7-15(31)8-6-14)29-20(34)16(24)4-3-9-27-23(25)26/h5-8,13,16-18,31H,3-4,9-12,24H2,1-2H3,(H,28,35)(H,29,34)(H,30,36)(H,32,33)(H4,25,26,27)/t16-,17-,18-/m0/s1 InChIKey=MQWUPCDMGPHONH-BZSNNMDCSA-N Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10053) the MBPDB database
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
4