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Peptide record

TPDB01652

ACE inhibitor ACE inhibitors Antioxidant standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB01652
ACE inhibitor
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB Multi-AOP
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
RYL
Physicochemical Analysis
C21H34N6O5
ANDCEQGHIKMFPSTWV
RLY
450.54
9.88
1
0
2
+1
-0.69
-0.667
130.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
330.72
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
3
C21H34N6O5
450.54
9.88
+1
-0.69
-0.667
450.5305
450.2583
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
3.31 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Liu L., Wei Y. N., Chang Q., Sun H. J., Chai K. G., Huang Z. Q., Zhao, Z. X., Zhao Z. X.
Ultrafast screening of a novel, moderately hydrophilic Angiotensin-converting-enzyme-inhibitory peptide, RYL, from silkworm pupa using an fe-doped-silkworm-excrement-derived biocarbon: waste conversion by waste. J. Agric. Food Chem., 65, 11202-11211,
2017
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(C)C)C(=O)O InChI=1S/C21H34N6O5/c1-12(2)10-17(20(31)32)27-19(30)16(11-13-5-7-14(28)8-6-13)26-18(29)15(22)4-3-9-25-21(23)24/h5-8,12,15-17,28H,3-4,9-11,22H2,1-2H3,(H,26,29)(H,27,30)(H,31,32)(H4,23,24,25)/t15-,16-,17-/m0/s1 InChIKey: CGWVCWFQGXOUSJ-ULQDDVLXSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001 Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10052) the MBPDB database
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
3