Peptide record

TPDB01648

Antibacterial Antioxidant Toxicity standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB01648
Antibacterial Antioxidant Toxicity
Anti-infective peptides Toxicity and safety peptides Functional / health-promoting peptides
dbAMP Peptipedia AnOxPePred - 1.0 AODB Multi-AOP
standard
No
A 3-aa standard natural multi-activity (Antibacterial, Antioxidant, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, AnOxPePred - 1.0, and other sources, with an available 3D structural model.
Sequence
RWW
Physicochemical Analysis
C28H34N8O4
ANDCEQGHILKMFPSTYV
W
546.63
11.05
1
0
2
+1
-2.89
-2.100
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
2012.33
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
3
C28H34N8O4
546.63
11.05
+1
-2.89
-2.100
Evidence Records 4 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
10% Hemolysis | >256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Ultra-short lipopeptides against gram-positive bacteria while alleviating antimicrobial resistance. | Eur J Med Chem | 2021
Evidence 2 Activity

Activity

10% Killing
Toxicity
64 µM
Cytotoxic
10% Killing | 64 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Ultra-short lipopeptides against gram-positive bacteria while alleviating antimicrobial resistance. | Eur J Med Chem | 2021
Evidence 3 Activity

Activity

18% Killing
Toxicity
128 µM
Cytotoxic
18% Killing | 128 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Ultra-short lipopeptides against gram-positive bacteria while alleviating antimicrobial resistance. | Eur J Med Chem | 2021
Evidence 4 Activity

Activity

10% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
10% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Ultra-short lipopeptides against gram-positive bacteria while alleviating antimicrobial resistance. | Eur J Med Chem | 2021