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Peptide record

TPDB01625

Antioxidative peptide Antioxidant standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB01625
Antioxidative peptide
Antioxidant
Functional / health-promoting peptides
AnOxPePred - 1.0 AODB AoXpDb Multi-AOP pep-lab Peptipedia
standard
No
A 10-aa standard natural antioxidant peptide sequence curated from AnOxPePred - 1.0, AODB, AoXpDb, and other sources, with an available 3D structural model.
Sequence
RPDFDLEPPY
Physicochemical Analysis
C58H81N13O18
ANCQGHIKMSTWV
P
1248.36
3.70
1
3
3
-2
4.01
-1.450
39.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
119.36
1
Residue Composition
number
0
A
1
R
0
N
2
D
0
C
1
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
3
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 2 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 3 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
10
C58H81N13O18
1248.36
3.70
-2
4.01
-1.450
1300 Da
3.75
0.00
N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)O
1248.33 Da
Evidence Records 1 records
Evidence 1 Activity

Activity

Antioxidative activity
The hydrolysates of yellowfin sole frame protein had both antioxidative activity and a synergistic effect with α-tocopherol using the linoleic acid in water/alcohol system. The peptide RPDFDLEPPY was isolated from the highest active fraction, so the peptide was a potential antioxidative peptide ( The antioxidative activity of pure peptide was not determined ).
Literature report: N.D Prediction: ToxinPred
Antioxidant

Assay & Model

linoleic acid peroxidation
Enzymatic hydrolysis
The yellowfin sole frame protein hydrolysate was prepared with mackerel intestines crude enzyme for 3 h at pH 10.0 and 50℃, and subsequently hydrolyzed with pepsin for 3 h at pH 2.0 and 37℃ after the pH of the solution had been adjusted to 2.0 with HCl.

Source & Reference

AODB AoXpDb
Park, P.-J., Jung, W.-K., Kim, S.-K., Jun, S.-Y. Purification and characterization of an antioxidative peptide from enzymatic hydrolysate of yellowfin sole ( Limanda aspera ) frame protein. European Food Research and Technology. 2004, 219, 20-6.
10.1007/s00217-004-0882-9
2004
DFBP

Other

Native peptide
Animal, Marine, Fish
Yellowfin sole (Limanda aspera, fish)
Yellowfin sole frame protein