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Peptide record

TPDB01620

ACE inhibitor from egg yolk protein dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) ACE inhibitors Antioxidant iDPPIV standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB01620
ACE inhibitor from egg yolk protein dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
ACE inhibitors Antioxidant iDPPIV
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB AoXpDb Multi-AOP iDPPIV
standard
No
A 9-aa standard natural multi-activity (ACE inhibitors, Antioxidant, and iDPPIV) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
RNDDLNYIQ
Physicochemical Analysis
C48H75N15O18
ACEGHKMFPSTWV
ND
1150.21
3.88
1
2
3
-1
2.88
-1.667
86.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
129.54
4
Residue Composition
number
0
A
1
R
2
N
2
D
0
C
0
E
1
Q
0
G
0
H
1
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 2 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
9
C48H75N15O18
1150.21
3.88
-1
2.88
-1.667
1150.1958
1149.5397
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
3.72 µM
ACE inhibitor
ah

Source & Reference

NA
Eckert E., Zambrowicz A., Pokora M., Setner B., Dąbrowska A., Szołtysik M., Szewczuk Z., Polanowski A., Trziszka T., Chrzanowska J.
Egg-yolk protein by-product as a source of ACE-inhibitory peptides obtained with using unconventional proteinase from Asian pumpkin (Cucurbita ficifolia). Journal of Proteomics 110, 107-116.
2014
Journal

Other

9
Activity expressed in (umol/L).
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB AoXpDb
DFBP
Evidence 3 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Zambrowicz A., Eckert E., Pokora M., Bobak Ł., Dąbrowska A., Szołtysik M., Trziszka T., Chrzanowska J.
Antioxidant and antidiabetic activities of peptides isolated from a hydrolysate of an egg-yolk protein by-product prepared with a proteinase from Asian pumpkin (Cucurbita ficifolia). RSC Adv. 5, 10460-10467.
2015
Journal

Other

9
Additional Detail Fields 1 fields
9