Peptide record

TPDB01584

Antibacterial Anticancer Antidiabetic Antifungal Antioxidant Antiparasitic Antiviral Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB01584
Antibacterial Anticancer Antidiabetic Antifungal Antioxidant Antiparasitic Antiviral Toxicity
Anti-infective peptides Cardiometabolic peptides Cancer-related peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb Multi-AOP ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antidiabetic, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RFIYMKGFGKPRFGKR
Physicochemical Analysis
C94H146N28O18S1
ANDCEQHLSTWV
RGKF
1988.43
12.15
6
0
6
+6
1.01
-0.906
24.38
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
74.93
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
0
L
3
K
1
M
3
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 0 K: 3 M: 1 F: 3 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
16
C94H146N28O18S1
1988.43
12.15
+6
1.01
-0.906
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against B. pyocyaneus (now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

active against B. pyocyaneus (now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against B. pyocyaneus (now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 5 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against B. pyocyaneus (now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against B. pyocyaneus (now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 8 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

active against B. pyocyaneus (now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
100 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
active against B. pyocyaneus (now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 11 Activity

Activity

MIC
Antiviral
25 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

active against B. pyocyaneus (now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
50 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

now P. aeruginosa) (MIC 25 ug/ml), E. coli (MIC 100 ug/ml), S. aureus (MIC 25 ug/ml), and C. albicans (MIC 50 ug/ml). Updated 5/2020 7/2021
Evidence 13 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs. | J Proteome Res | 2012