Back to search

Peptide record

TPDB01569

ACE inhibitor from egg yolk protein dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) ACE inhibitors Antioxidant iDPPIV standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB01569
ACE inhibitor from egg yolk protein dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
ACE inhibitors Antioxidant iDPPIV
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB AoXpDb Multi-AOP iDPPIV
standard
No
A 9-aa standard natural multi-activity (ACE inhibitors, Antioxidant, and iDPPIV) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
RASDPLLSV
Physicochemical Analysis
C41H72N12O14
NCEQGHIKMFTWY
LS
957.09
6.78
1
1
4
-0
1.53
0.267
130.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
1
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
0
K
0
M
0
F
1
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
9
C41H72N12O14
957.09
6.78
-0
1.53
0.267
957.0795
956.5274
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
4.70 µM
ACE inhibitor
ah

Source & Reference

NA
Eckert E., Zambrowicz A., Pokora M., Setner B., Dąbrowska A., Szołtysik M., Szewczuk Z., Polanowski A., Trziszka T., Chrzanowska J.
Egg-yolk protein by-product as a source of ACE-inhibitory peptides obtained with using unconventional proteinase from Asian pumpkin (Cucurbita ficifolia). Journal of Proteomics 110, 107-116.
2014
Journal

Other

9
Activity expressed in (umol/L).
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB AoXpDb
DFBP
Evidence 3 Activity

Activity

IC50
iDPPIV
426.25 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Zambrowicz A., Eckert E., Pokora M., Bobak Ł., Dąbrowska A., Szołtysik M., Trziszka T., Chrzanowska J.
Antioxidant and antidiabetic activities of peptides isolated from a hydrolysate of an egg-yolk protein by-product prepared with a proteinase from Asian pumpkin (Cucurbita ficifolia). RSC Adv. 5, 10460-10467.
2015
Journal

Other

9
Additional Detail Fields 1 fields
9