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Peptide record

TPDB01565

Antihypertensive peptide derived from egg white Antihypertensive Antioxidant standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB01565
Antihypertensive peptide derived from egg white
Antihypertensive Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
AHTPDB AHTpin Peptipedia AnOxPePred - 1.0 AODB AoXpDb Multi-AOP
standard
No
A 5-aa standard natural multi-activity (Antihypertensive and Antioxidant) peptide sequence curated from AHTPDB, AHTpin, Peptipedia, and other sources, with an available 3D structural model.
Sequence
RADHP
Physicochemical Analysis
C24H38N10O8
NCEQGILKMFSTWYV
ARDHP
594.63
7.85
2
1
1
+0
3.28
-2.200
20.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
1
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C24H38N10O8
594.63
7.85
+0
3.28
-2.200
594.6192
594.2866
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
Antihypertensive
0.00 µM
Lowering blood pressure in vivo in rats
hypotensive
hyp

Source & Reference

AHTPDB
Miguel M., Ramos M., Aleixandre M.A., López-Fandino R.
Antihypertensive peptides obtained from egg white proteins by enzymatic hydrolysis, stability under simulated gastrointestinal digestion. J. Agric. Food Chem., Vol. 54, No. 3, 726-731, 2006
2006
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=C[N]([H])C=N1)C(=O)N2[C@@H](CCC2)C(=O)O InChI=1S/C24H38N10O8/c1-12(31-20(38)14(25)4-2-6-29-24(26)27)19(37)32-15(9-18(35)36)21(39)33-16(8-13-10-28-11-30-13)22(40)34-7-3-5-17(34)23(41)42/h10-12,14-17H,2-9,25H2,1H3,(H,28,30)(H,31,38)(H,32,37)(H,33,39)(H,35,36)(H,41,42)(H4,26,27,29)/t12-,14-,15-,16-,17-/m0/s1 InChIKey=GMZGWULVRBHSMA-SRQBIAJPSA-N
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB AoXpDb
DFBP
Additional Detail Fields 1 fields
5