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Peptide record

TPDB01520

ACE inhibitor from egg white ovalbumin ACE inhibitors Antihypertensive Antioxidant standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB01520
ACE inhibitor from egg white ovalbumin
ACE inhibitors Antihypertensive Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AHTPDB AHTpin AODB Multi-AOP
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, and Antioxidant) peptide sequence curated from Peptipedia, AHTPDB, AHTpin, and other sources, with an available 3D structural model.
Sequence
QIGLF
Physicochemical Analysis
C28H44N6O7
ARNDCEHKMPSTWYV
QGILF
576.69
6.02
0
0
3
-0
-1.41
1.440
156.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C28H44N6O7
576.69
6.02
-0
-1.41
1.440
576.6832
576.3261
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Yu Z,, Zhao W., Liu J., Lu J., Chen F.
QIGLF, a novel angiotensin I-converting enzyme-inhibitory peptide from egg white protein. J. Sci. Food. Agric., 91(5), 921-926, 2011
2011
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O InChI=1S/C28H44N6O7/c1-5-17(4)24(34-25(37)19(29)11-12-22(30)35)27(39)31-15-23(36)32-20(13-16(2)3)26(38)33-21(28(40)41)14-18-9-7-6-8-10-18/h6-10,16-17,19-21,24H,5,11-15,29H2,1-4H3,(H2,30,35)(H,31,39)(H,32,36)(H,33,38)(H,34,37)(H,40,41)/t17-,19-,20-,21-,24-/m0/s1 InChIKey=MTSHVTAATUWGIO-ZKEZPVKKSA-N Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9411) Predicted ligand of ubiquitin ligase (XIAP) (EC 2.3.2.27) (Alpha Fold ID AF-P98170-F1-model-v2) according to the BIOPEP-UWM Virtual database (ID 281)
Evidence 2 Activity

Activity

IC50
Antihypertensive
0.00 µM
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

AHTPDB
Yu Z,, Zhao W., Liu J., Lu J., Chen F.
QIGLF, a novel angiotensin I-converting enzyme-inhibitory peptide from egg white protein. J. Sci. Food. Agric., 91(5), 921-926, 2011
2011
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O InChI=1S/C28H44N6O7/c1-5-17(4)24(34-25(37)19(29)11-12-22(30)35)27(39)31-15-23(36)32-20(13-16(2)3)26(38)33-21(28(40)41)14-18-9-7-6-8-10-18/h6-10,16-17,19-21,24H,5,11-15,29H2,1-4H3,(H2,30,35)(H,31,39)(H,32,36)(H,33,38)(H,34,37)(H,40,41)/t17-,19-,20-,21-,24-/m0/s1 InChIKey=MTSHVTAATUWGIO-ZKEZPVKKSA-N Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9411) Predicted ligand of ubiquitin ligase (XIAP) (EC 2.3.2.27) (Alpha Fold ID AF-P98170-F1-model-v2) according to the BIOPEP-UWM Virtual database (ID 281)
Evidence 3 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
5