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Peptide record

TPDB01465

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Antibacterial Anticancer Antifungal Antioxidant Toxicity iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB01465
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Antibacterial Anticancer Antifungal Antioxidant Toxicity iDPPIV
Anti-infective peptides Cardiometabolic peptides Cancer-related peptides Toxicity and safety peptides Functional / health-promoting peptides
Peptipedia CAFPdb dbAMP AnOxPePred - 1.0 AODB Multi-AOP iDPPIV
standard
No
A 2-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
PW
Physicochemical Analysis
C16H19N3O3
ARNDCEQGHILKMFSTYV
PW
301.35
6.02
0
0
1
-0
-1.40
-1.250
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
1825.15
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
2
C16H19N3O3
301.35
6.02
-0
-1.40
-1.250
301.3396
301.1422
Evidence Records 3 records
Evidence 1 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human fibroblasts

Target

Human fibroblasts

Source & Reference

NA
DBAASP
Cyclic dipeptides from rhabditid entomopathogenic nematode-associated Bacillus cereus have antimicrobial activities. | World J Microbiol Biotechnol | 2014
Evidence 3 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N1[C@@H](CCC1)C(=O)N[C@@H](CC2=C[N]([H])C3=CC=CC=C23)C(=O)O InChI=1S/C16H19N3O3/c20-15(13-6-3-7-17-13)19-14(16(21)22)8-10-9-18-12-5-2-1-4-11(10)12/h1-2,4-5,9,13-14,17-18H,3,6-8H2,(H,19,20)(H,21,22)/t13-,14-/m0/s1 InChIKey=UEKYKRQIAQHOOZ-KBPBESRZSA-N Antioxidative peptide according to the BIOPEP-UWM database of bioacttive peptides (ID 8190) the PlantPepDB database
Additional Detail Fields 1 fields
2