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Peptide record

TPDB01325

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Antihypertensive Antioxidant Umami iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB01325
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Antihypertensive Antioxidant Umami iDPPIV
Cardiometabolic peptides Food sensory peptides Functional / health-promoting peptides
AHTPDB AHTpin Peptipedia AODB Multi-AOP Tastepeptides-Meta iDPPIV
standard
No
A 2-aa standard natural multi-activity (Antihypertensive, Antioxidant, Umami, and other sources) peptide sequence curated from AHTPDB, AHTpin, Peptipedia, and other sources, with an available 3D structural model.
Sequence
NP
Physicochemical Analysis
C9H15N3O4
ARDCEQGHILKMFSTWYV
NP
229.24
6.02
0
0
0
-0
0.87
-2.550
0.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C9H15N3O4
229.24
6.02
-0
0.87
-2.550
229.2325
229.1059
Evidence Records 2 records
Evidence 1 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Evidence 2 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Hikida A., Ito K., Motoyama T., Kato R., Kawarasaki Y.
Systematic analysis of a dipeptide library for inhibitor development using human dipeptidyl peptidase IV produced by a Saccharomyces cerevisiae expression system. Biochemical and Biophysical Research Communications 430, 1217-1222, 2013
2013
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C9H15N3O4/c10-5(4-7(11)13)8(14)12-3-1-2-6(12)9(15)16/h5-6H,1-4,10H2,(H2,11,13)(H,15,16)/t5-,6-/m0/s1 InChIKey=GADKFYNESXNRLC-WDSKDSINSA-N Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database the EROP-Moscow database Umami peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 530)
Additional Detail Fields 1 fields
2