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Peptide record

TPDB01314

Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB01314
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 35-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
NKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
Physicochemical Analysis
C152H234N38O46S3
RQHMY
G
3425.94
3.70
1
3
15
-2
-0.95
0.691
89.43
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
5625
164.19
7
Residue Composition
number
5
A
0
R
1
N
2
D
3
C
1
E
0
Q
7
G
0
H
3
I
3
L
1
K
0
M
2
F
2
P
1
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 2 C: 3 E: 1 Q: 0 G: 7 H: 0 I: 3 L: 3 K: 1 M: 0 F: 2 P: 2 S: 1 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
35
C152H234N38O46S3
3425.94
3.70
-2
-0.95
0.691
Evidence Records 24 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16 µM

Target

B. anthracis

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monoc
Evidence 2 Activity

Activity

MIC
Antibacterial
40 µM

Target

B. thuringiensis

Source & Reference

dbAMP DRAMP

Other

Active against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MI
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µM

Target

S. carnosus

Source & Reference

dbAMP DRAMP

Other

e against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 25
Evidence 4 Activity

Activity

MIC
Antibacterial
40 µM

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP

Other

C 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal
Evidence 5 Activity

Activity

MIC
Antibacterial
100 µM

Target

Streptococcus pyogenes

Source & Reference

dbAMP DRAMP

Other

sis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal effect (Silkin L Bioorg Med C
Evidence 6 Activity

Activity

MIC
Antibacterial
250 µM

Target

B.subtilis

Source & Reference

dbAMP DRAMP

Other

nosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal effect (Silkin L Bioorg Med Chem Lett. 2008 May 15 18(10):3103-6
Evidence 7 Activity

Activity

MIC
Antifungal
16 µM

Target

B. anthracis

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monoc
Evidence 8 Activity

Activity

MIC
Antifungal
40 µM

Target

B. thuringiensis

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MI
Evidence 9 Activity

Activity

MIC
Antifungal
100 µM

Target

S. carnosus

Source & Reference

dbAMP DRAMP Antifungipept

Other

e against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 25
Evidence 10 Activity

Activity

MIC
Antifungal
40 µM

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP Antifungipept

Other

C 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal
Evidence 11 Activity

Activity

MIC
Antifungal
100 µM

Target

Streptococcus pyogenes

Source & Reference

dbAMP DRAMP Antifungipept

Other

sis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal effect (Silkin L Bioorg Med C
Evidence 12 Activity

Activity

MIC
Antifungal
250 µM

Target

B.subtilis

Source & Reference

dbAMP DRAMP Antifungipept

Other

nosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal effect (Silkin L Bioorg Med Chem Lett. 2008 May 15 18(10):3103-6
Evidence 13 Activity

Activity

MIC
Antiparasitic
16 µM

Target

B. anthracis

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monoc
Evidence 14 Activity

Activity

MIC
Antiparasitic
40 µM

Target

B. thuringiensis

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MI
Evidence 15 Activity

Activity

MIC
Antiparasitic
100 µM

Target

S. carnosus

Source & Reference

dbAMP 3.0 DRAMP

Other

e against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 25
Evidence 16 Activity

Activity

MIC
Antiparasitic
40 µM

Target

L. monocytogenes

Source & Reference

dbAMP 3.0 DRAMP

Other

C 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal
Evidence 17 Activity

Activity

MIC
Antiparasitic
100 µM

Target

Streptococcus pyogenes

Source & Reference

dbAMP 3.0 DRAMP

Other

sis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal effect (Silkin L Bioorg Med C
Evidence 18 Activity

Activity

MIC
Antiparasitic
250 µM

Target

B.subtilis

Source & Reference

dbAMP 3.0 DRAMP

Other

nosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal effect (Silkin L Bioorg Med Chem Lett. 2008 May 15 18(10):3103-6
Evidence 19 Activity

Activity

MIC
Antiviral
16 µM

Target

B. anthracis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monoc
Evidence 20 Activity

Activity

MIC
Antiviral
40 µM

Target

B. thuringiensis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Active against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MI
Evidence 21 Activity

Activity

MIC
Antiviral
100 µM

Target

S. carnosus

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

e against B. anthracis (MIC 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 25
Evidence 22 Activity

Activity

MIC
Antiviral
40 µM

Target

L. monocytogenes

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

C 16 uM), B. cereus, B. thuringiensis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal
Evidence 23 Activity

Activity

MIC
Antiviral
100 µM

Target

Streptococcus pyogenes

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

sis (MIC 40 uM), E. faecalis, S. carnosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal effect (Silkin L Bioorg Med C
Evidence 24 Activity

Activity

MIC
Antiviral
250 µM

Target

B.subtilis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

nosus (MIC 100 uM), L. monocytogenes (MIC 40 uM), and S. pyogenes (MIC 100 uM). Inactive: B.subtilis (MIC 250 uM). It also has spermicidal effect (Silkin L Bioorg Med Chem Lett. 2008 May 15 18(10):3103-6