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Peptide record

TPDB01264

ACE inhibitor ACE inhibitors Antioxidant standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB01264
ACE inhibitor
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AODB AoXpDb Multi-AOP
standard
No
A 6-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from Peptipedia, AODB, AoXpDb, and other sources, with an available 3D structural model.
Sequence
MPACGS
Physicochemical Analysis
C21H36N6O8S2
RNDEQHILKFTWYV
ACGMPS
564.67
5.33
0
0
2
-0
-0.05
0.567
16.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
1
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
1
M
0
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 1 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C21H36N6O8S2
564.67
5.33
-0
-0.05
0.567
564.6767
564.2028
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
191.50 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Luna-Vital D. A., Gonzalez de Mejia E., Mendoza S., Loarca-Pina G.
Peptides present in the non-digestible fraction of common beans (Phaseolus vulgaris L.) inhibit the angiotensin-I converting enzyme by interacting with its catalytic cavity independent of their antioxidant capacity. Food Funct., 6, 1470-1479, 2015
2015
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCSC)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CS)C(=O)NCC(=O)N[C@@]([H])(CO)C(=O)O InChI=1S/C17H28N6O10/c1-8(17(32)33)21-12(26)5-20-16(31)10(7-24)23-13(27)6-19-15(30)9(2-3-14(28)29)22-11(25)4-18/h8-10,24H,2-7,18H2,1H3,(H,19,30)(H,20,31)(H,21,26)(H,22,25)(H,23,27)(H,28,29)(H,32,33)/t8-,9-,10-/m0/s1 InChIKey: XIBQWYMZJHKUKI-YTFOTSKYSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001 Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9106)
Additional Detail Fields 1 fields
6