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Peptide record

TPDB01149

ACE inhibitor ACE inhibitors Antioxidant Bitter standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB01149
ACE inhibitor
ACE inhibitors Antioxidant Bitter
Cardiometabolic peptides Food sensory peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB Multi-AOP Tastepeptides-Meta
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors, Antioxidant, and Bitter) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
LQL
Physicochemical Analysis
C17H32N4O5
ARNDCEGHIKMFPSTWYV
L
372.46
6.02
0
0
2
-0
-0.54
1.367
260.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
2
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C17H32N4O5
372.46
6.02
-0
-0.54
1.367
372.4585
372.2365
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Girgih AT, He R, Malomo SA, Offengenden M, Wu J, Aluko RE.
Structural and functional characterization of hemp seed (Cannabis sativa L.) protein-derived antioxidant and antihypertensive peptides. J. Funct. Foods 6, 384–394.
2014
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)O InChI= 1S/C17H32N4O5/c1-9(2)7-11(18)15(23)20-12(5-6-14(19)22)16(24)21-13(17(25)26)8-10(3)4/h9-13H,5-8,18H2,1-4H3,(H2,19,22)(H,20,23)(H,21,24)(H,25,26)/t11-,12-,13-/m0/s1 InChIKey: LOLUPZNNADDTAA-AVGNSLFASA-N Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10003) Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007) according to the BIOPEP-UWM database of bioactive peptides (ID 10005) Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 494) the ChEMBL database
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
3