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Peptide record

TPDB01143

ACE inhibitor ACE inhibitors Antioxidant standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB01143
ACE inhibitor
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB Multi-AOP
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
LPYY
Physicochemical Analysis
C29H38N4O7
ARNDCEQGHIKMFSTWV
Y
554.64
5.88
0
0
3
-0
-1.99
-0.100
97.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
2980
537.28
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
4
C29H38N4O7
554.64
5.88
-0
-1.99
-0.100
554.6331
554.2731
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
116.26 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Li J., Su J., Chen M., Chen J., Ding W., Li Y., Yin H.
Two novel potent ACEI peptides isolated from Pinctada fucata meat hydrolysates using in silico analysis: identification, screening and inhibitory mechanisms. RSC Adv., 11, 12172-12182, 2021
2021
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: [C@H](N)(CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(O)=O InChI=1S/C29H38N4O7/c1-17(2)14-22(30)28(38)33-13-3-4-25(33)27(37)31-23(15-18-5-9-20(34)10-6-18)26(36)32-24(29(39)40)16-19-7-11-21(35)12-8-19/h5-12,17,22-25,34-35H,3-4,13-16,30H2,1-2H3,(H,31,37)(H,32,36)(H,39,40)/t22-,23-,24-,25-/m0/s1 InChIKey=FZHFSHYCWQZWFU-QORCZRPOSA-N Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3309)
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
4