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Peptide record

TPDB01102

Antioxidative peptide P4 Antioxidant standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB01102
Antioxidative peptide P4
Antioxidant
Functional / health-promoting peptides
AnOxPePred - 1.0 AODB AoXpDb Multi-AOP pep-lab Peptipedia
standard
No
A 10-aa standard natural antioxidant peptide sequence curated from AnOxPePred - 1.0, AODB, AoXpDb, and other sources, with an available 3D structural model.
Sequence
LLPHHADADY
Physicochemical Analysis
C52H74N14O16
RNCEQGIKMFSTWV
ADHL
1151.24
4.93
2
2
5
-2
2.43
-0.510
98.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
129.43
1
Residue Composition
number
2
A
0
R
0
N
2
D
0
C
0
E
0
Q
0
G
2
H
0
I
2
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 0 H: 2 I: 0 L: 2 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
10
C52H74N14O16
1151.24
4.93
-2
2.43
-0.510
1151.9 Da
4.96
0.00
N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)O
1151.22 Da
Evidence Records 1 records
Evidence 1 Activity

Activity

Antioxidative activity
This peptide yielded antioxidative activity against the peroxidation of linoleic acid in an aqueous system at pH 7.0. The antioxidative activity was measured with 69 μg of P4 and the peptide concentrations ranged from 3.3 × 10^-7 to 4.5 × 10^-5 M, in which range the antioxidative activity was dose dependent and no prooxidative activity was observed (data not shown).
Literature report: N.D Prediction: ToxinPred
Antioxidant

Assay & Model

linoleic acid peroxidation
Enzymatic hydrolysis
Peptide obtained by hydrolysis of a soybean β-conglycinin (7S protein) by use of protease S.

Source & Reference

AODB AoXpDb
Chen, H.-M., Muramoto, K., Yamauchi, F. Structural Analysis of Antioxidative Peptides from Soybean .beta.-Conglycinin. Journal of Agricultural and Food Chemistry. 1995, 43, 574-8.
10.1021/jf00051a004
[1] Chen H M, Muramoto K, Yamauchi F, et al. Antioxidant Activity of Designed Peptides Based on the Antioxidative Peptide Isolated from Digests of a Soybean Protein[J]. Journal of Agricultural & Food Chemistry, 1996, 44(9):2619-2623. [2] Huaming Chen †, Koji Muramoto , †, Fumio Yamauchi †, et al. Antioxidative Properties of Histidine-Containing Peptides Designed from Peptide Fragments Found in the Digests of a Soybean Protein.[J]. Journal of Agricultural & Food Chemistry, 1998, 46(1):49.
1995
DFBP

Other

Native peptide
Plant
Soybean protein
β-Conglycinin (7S protein)