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Peptide record

TPDB01070

Antibacterial Antifungal Antioxidant Bitter Hemolysis Toxicity standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB01070
Antibacterial Antifungal Antioxidant Bitter Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Food sensory peptides Functional / health-promoting peptides
Peptipedia CAFPdb dbAMP AnOxPePred - 1.0 AODB Multi-AOP Tastepeptides-Meta PD_Hemolysis
standard
No
A 2-aa standard natural multi-activity (Antibacterial, Antifungal, Antioxidant, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
LK
Physicochemical Analysis
C12H25N3O3
ARNDCEQGHIMFPSTWYV
LK
259.35
10.10
1
0
1
+1
0.43
-0.050
195.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C12H25N3O3
259.35
10.10
+1
0.43
-0.050
Evidence Records 5 records
Evidence 1 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
50% Hemolysis | 15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Site-Specific Isopeptide Bond Formation: A Powerful Tool for the Generation of Potent and Nontoxic Antimicrobial Peptides. | J Med Chem | 2022
Evidence 3 Activity

Activity

50% Cell death
Toxicity
55 µM
Cytotoxic
50% Cell death | 55 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Site-Specific Isopeptide Bond Formation: A Powerful Tool for the Generation of Potent and Nontoxic Antimicrobial Peptides. | J Med Chem | 2022
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
<<12.5 µM
Hemolytic Cytotoxic
50% Hemolysis | <<12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Small lipopeptides possess anti-biofilm capability comparable to daptomycin and vancomycin. | RSC Adv | 2015
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis