Peptide record

TPDB01011

ACE inhibitor ACE inhibitors Antioxidant standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB01011
ACE inhibitor
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB AoXpDb Multi-AOP
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
LEEAF
Physicochemical Analysis
C28H41N5O10
RNDCQGHIKMPSTWYV
E
607.66
3.13
0
2
3
-2
2.18
0.280
98.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
2
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C28H41N5O10
607.66
3.13
-2
2.18
0.280
607.6510
607.2843
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Girgih AT, He R, Malomo SA, Offengenden M, Wu J, Aluko RE.
Structural and functional characterization of hemp seed (Cannabis sativa L.) protein-derived antioxidant and antihypertensive peptides. J. Funct. Foods 6, 384–394.
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O InChI= 1S/C28H41N5O10/c1-15(2)13-18(29)25(39)31-20(10-12-23(36)37)27(41)32-19(9-11-22(34)35)26(40)30-16(3)24(38)33-21(28(42)43)14-17-7-5-4-6-8-17/h4-8,15-16,18-21H,9-14,29H2,1-3H3,(H,30,40)(H,31,39)(H,32,41)(H,33,38)(H,34,35)(H,36,37)(H,42,43)/t16-,18-,19-,20-,21-/m0/s1 InChIKey: BEHNCPVERZALFE-MQBSTWLZSA-N Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9994) Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007) according to the BIOPEP-UWM database of bioactive peptides (ID 9996)
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB AoXpDb
DFBP
Additional Detail Fields 1 fields
5