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Peptide record

TPDB00969

Antibacterial Anticancer Antifungal Antioxidant Antiparasitic standard
44 amino acids
Basic Information
3D PDB MODEL
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TPDB00969
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic
Anti-infective peptides Cancer-related peptides Functional / health-promoting peptides
AntiBP3 dbAMP DRAMP Peptipedia dbACP Antifungipept
standard
No
A 44-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KYYGNGVTCGKHSCSVDWGKATTCIINNGAMAWATGGHQGNHKC
Physicochemical Analysis
C196H297N61O60S5
RELFP
G
4628.19
8.69
7
1
13
+3
3.30
-0.493
40.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
14230
307.46
17
Residue Composition
number
4
A
0
R
4
N
1
D
4
C
0
E
1
Q
8
G
3
H
2
I
0
L
4
K
1
M
0
F
0
P
2
S
4
T
2
W
2
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 4 D: 1 C: 4 E: 0 Q: 1 G: 8 H: 3 I: 2 L: 0 K: 4 M: 1 F: 0 P: 0 S: 2 T: 4 W: 2 Y: 2 V: 2
Chemical Descriptors
44
C196H297N61O60S5
4628.19
8.69
+3
3.30
-0.493
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.8 µM

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
d L. monocytogenes CIP 82.110 (MIC 512 nM) ( Makhloufi KM et al., 2013 ). The MIC against L. monocytogenes (MIC 6.8 uM) for a synthetic form of pediocin PA-1, similar to the natural form. Also active against E
Evidence 2 Activity

Activity

MIC
Antifungal
6.8 µM

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
d L. monocytogenes CIP 82.110 (MIC 512 nM) ( Makhloufi KM et al., 2013 ). The MIC against L. monocytogenes (MIC 6.8 uM) for a synthetic form of pediocin PA-1, similar to the natural form. Also active against E
Evidence 3 Activity

Activity

MIC
Antiparasitic
6.8 µM

Target

L. monocytogenes

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
d L. monocytogenes CIP 82.110 (MIC 512 nM) ( Makhloufi KM et al., 2013 ). The MIC against L. monocytogenes (MIC 6.8 uM) for a synthetic form of pediocin PA-1, similar to the natural form. Also active against E