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Peptide record

TPDB00968

ACE inhibitor from wakame KYY ACE inhibitors Antihypertensive Antioxidant Selfassembly standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB00968
ACE inhibitor from wakame KYY
ACE inhibitors Antihypertensive Antioxidant Selfassembly
Cardiometabolic peptides Functional / health-promoting peptides Self-assembling and biomaterial peptides
Peptipedia AHTPDB AHTpin AnOxPePred - 1.0 AODB Multi-AOP SAPdb
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, Antioxidant, and other sources) peptide sequence curated from Peptipedia, AHTPDB, AHTpin, and other sources, with an available 3D structural model.
Sequence
KYY
Physicochemical Analysis
C24H32N4O6
ARNDCEQGHILMFPSTWV
Y
472.54
9.56
1
0
2
+1
-0.89
-2.167
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
2980
630.63
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
3
C24H32N4O6
472.54
9.56
+1
-0.89
-2.167
472.5328
472.2314
Self-Assembly Information 1 records
Record 1 Selfassembly

Source

25515887
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel
pH: 7 temperature: Room temperature solvent: water concentration: 30mMol/L
Selfassembly; Nanostructure=Hydrogel; Trigger=pH: 7; temperature: Room temperature; solvent: water; concentration: 30mMol/L
Transmission Electron Microscopy (TEM), DLS (Dynamic Light Scattering) and FTIR (Fourier Transform Infrared)
Selfassembly
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
79.00 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

3
Evidence 2 Activity

Activity

IC50
Antihypertensive
79.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
3
Evidence 3 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Trigger=pH: 7 temperature: Room temperature solvent: water concentration: 30mMol/L
Hydrogel

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

None specified
pH: 7 temperature: Room temperature solvent: water concentration: 30mMol/L
Transmission Electron Microscopy (TEM), DLS (Dynamic Light Scattering) and FTIR (Fourier Transform Infrared)
25515887
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Additional Detail Fields 6 fields
pH: 7 temperature: Room temperature solvent: water concentration: 30mMol/L
None specified
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
3
25515887
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly