Peptide record

TPDB00954

ACE inhibitor ACE inhibitors Antioxidant standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB00954
ACE inhibitor
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AODB AoXpDb
standard
No
A 7-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from Peptipedia, AODB, and AoXpDb, with an available 3D structural model.
Sequence
KVEGDLK
Physicochemical Analysis
C34H61N9O12
ARNCQHIMFPSTWY
K
787.91
6.99
2
2
2
-0
4.75
-1.029
97.14
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
1
E
0
Q
1
G
0
H
0
I
1
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C34H61N9O12
787.91
6.99
-0
4.75
-1.029
787.8988
787.4425
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
4.66 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Zielińska E., Karaś M., Baraniak B., Jakubczyk A.
Evaluation of ACE, alpha‑glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020
2020
Journal

Other

7
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)O InChI=1S/C34H61N9O12/c1-18(2)15-23(31(51)41-22(34(54)55)10-6-8-14-36)42-32(52)24(16-27(47)48)39-25(44)17-38-30(50)21(11-12-26(45)46)40-33(53)28(19(3)4)43-29(49)20(37)9-5-7-13-35/h18-24,28H,5-17,35-37H2,1-4H3,(H,38,50)(H,39,44)(H,40,53)(H,41,51)(H,42,52)(H,43,49)(H,45,46)(H,47,48)(H,54,55)/t20-,21-,22-,23-,24-,28-/m0/s1 InChIKey=USIFMUVFRAKZRH-BIWWIESBSA-N Inhibitor of pancreatic lipase according to the BIOPEP-UWM database of bioactive peptides (ID 9824) Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9825) Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9439)
Additional Detail Fields 1 fields
7