Back to search

Peptide record

TPDB00864

Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB00864
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 dbAMP DRAMP Peptipedia SATPdb Antifungipept
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ITSISLCTPGCKTGALMGCNMKTATCHCSIHVSK
Physicochemical Analysis
C143H246N42O45S7
RDEQFWY
CT
3498.20
8.48
5
0
10
+3
3.03
0.415
71.76
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
250
7.15
15
Residue Composition
number
2
A
0
R
1
N
0
D
5
C
0
E
0
Q
3
G
2
H
3
I
2
L
3
K
2
M
0
F
1
P
4
S
5
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 5 E: 0 Q: 0 G: 3 H: 2 I: 3 L: 2 K: 3 M: 2 F: 0 P: 1 S: 4 T: 5 W: 0 Y: 0 V: 1
Chemical Descriptors
34
C143H246N42O45S7
3498.20
8.48
+3
3.03
0.415
Evidence Records 20 records
Evidence 1 Activity

Activity

MIC
Antibacterial
83.6 µg/mL

Target

A. viscosus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
spp., Streptococcus spp., Bacillus spp. (MIC 4.2-8.4), Clostridium spp. (MIC 1.1 ug/ml), A. viscosus (MIC 83.6 ug/ml), Peptostreptococcus spp., C. diphtheriae, G. vaginalis, M. smegmatis, P. acnes (MIC 2.1-8
Evidence 2 Activity

Activity

MIC
Antibacterial
2.1-8.4 µg/mL

Target

P. acnes

Source & Reference

dbAMP DRAMP

Other

us (MIC 83.6 ug/ml), Peptostreptococcus spp., C. diphtheriae, G. vaginalis, M. smegmatis, P. acnes (MIC 2.1-8.4 ug/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. in
Evidence 3 Activity

Activity

MIC
Antibacterial
1.1 µg/mL

Target

C. jejune

Source & Reference

dbAMP DRAMP

Other

is, P. acnes (MIC 2.1-8.4 ug/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug
Evidence 4 Activity

Activity

MIC
Antibacterial
66.9 µg/mL

Target

H. influenzae

Source & Reference

dbAMP DRAMP

Other

g/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug/ml). It also has spermicidal ef
Evidence 5 Activity

Activity

MIC
Antibacterial
0.3 µg/mL

Target

H. pylori

Source & Reference

dbAMP DRAMP

Other

s or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug/ml). It also has spermicidal effect. Antibiofilm:bacteria:
Evidence 6 Activity

Activity

MIC
Antifungal
83.6 µg/mL

Target

A. viscosus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
spp., Streptococcus spp., Bacillus spp. (MIC 4.2-8.4), Clostridium spp. (MIC 1.1 ug/ml), A. viscosus (MIC 83.6 ug/ml), Peptostreptococcus spp., C. diphtheriae, G. vaginalis, M. smegmatis, P. acnes (MIC 2.1-8
Evidence 7 Activity

Activity

MIC
Antifungal
2.1-8.4 µg/mL

Target

P. acnes

Source & Reference

dbAMP DRAMP Antifungipept

Other

us (MIC 83.6 ug/ml), Peptostreptococcus spp., C. diphtheriae, G. vaginalis, M. smegmatis, P. acnes (MIC 2.1-8.4 ug/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. in
Evidence 8 Activity

Activity

MIC
Antifungal
1.1 µg/mL

Target

C. jejune

Source & Reference

dbAMP DRAMP Antifungipept

Other

is, P. acnes (MIC 2.1-8.4 ug/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug
Evidence 9 Activity

Activity

MIC
Antifungal
66.9 µg/mL

Target

H. influenzae

Source & Reference

dbAMP DRAMP Antifungipept

Other

g/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug/ml). It also has spermicidal ef
Evidence 10 Activity

Activity

MIC
Antifungal
0.3 µg/mL

Target

H. pylori

Source & Reference

dbAMP DRAMP Antifungipept

Other

s or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug/ml). It also has spermicidal effect. Antibiofilm:bacteria:
Evidence 11 Activity

Activity

MIC
Antiparasitic
83.6 µg/mL

Target

A. viscosus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
spp., Streptococcus spp., Bacillus spp. (MIC 4.2-8.4), Clostridium spp. (MIC 1.1 ug/ml), A. viscosus (MIC 83.6 ug/ml), Peptostreptococcus spp., C. diphtheriae, G. vaginalis, M. smegmatis, P. acnes (MIC 2.1-8
Evidence 12 Activity

Activity

MIC
Antiparasitic
2.1-8.4 µg/mL

Target

P. acnes

Source & Reference

DRAMP

Other

us (MIC 83.6 ug/ml), Peptostreptococcus spp., C. diphtheriae, G. vaginalis, M. smegmatis, P. acnes (MIC 2.1-8.4 ug/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. in
Evidence 13 Activity

Activity

MIC
Antiparasitic
1.1 µg/mL

Target

C. jejune

Source & Reference

DRAMP

Other

is, P. acnes (MIC 2.1-8.4 ug/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug
Evidence 14 Activity

Activity

MIC
Antiparasitic
66.9 µg/mL

Target

H. influenzae

Source & Reference

DRAMP

Other

g/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug/ml). It also has spermicidal ef
Evidence 15 Activity

Activity

MIC
Antiparasitic
0.3 µg/mL

Target

H. pylori

Source & Reference

DRAMP

Other

s or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug/ml). It also has spermicidal effect. Antibiofilm:bacteria:
Evidence 16 Activity

Activity

MIC
Antiviral
83.6 µg/mL

Target

A. viscosus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
spp., Streptococcus spp., Bacillus spp. (MIC 4.2-8.4), Clostridium spp. (MIC 1.1 ug/ml), A. viscosus (MIC 83.6 ug/ml), Peptostreptococcus spp., C. diphtheriae, G. vaginalis, M. smegmatis, P. acnes (MIC 2.1-8
Evidence 17 Activity

Activity

MIC
Antiviral
2.1-8.4 µg/mL

Target

P. acnes

Source & Reference

DRAMP

Other

us (MIC 83.6 ug/ml), Peptostreptococcus spp., C. diphtheriae, G. vaginalis, M. smegmatis, P. acnes (MIC 2.1-8.4 ug/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. in
Evidence 18 Activity

Activity

MIC
Antiviral
1.1 µg/mL

Target

C. jejune

Source & Reference

DRAMP

Other

is, P. acnes (MIC 2.1-8.4 ug/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug
Evidence 19 Activity

Activity

MIC
Antiviral
66.9 µg/mL

Target

H. influenzae

Source & Reference

DRAMP

Other

g/ml) (Ref see AP1003), S. aureus or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug/ml). It also has spermicidal ef
Evidence 20 Activity

Activity

MIC
Antiviral
0.3 µg/mL

Target

H. pylori

Source & Reference

DRAMP

Other

s or MRSA, and Gram- bacteria: C. jejune (MIC 1.1 ug/ml), H. influenzae (MIC 66.9 ug/ml), H. pylori (MIC 0.3 ug/ml), and Neisseria spp (MIC 8.4 ug/ml). It also has spermicidal effect. Antibiofilm:bacteria: