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Peptide record

TPDB00837

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) ACE inhibitors Antioxidant iDPPIV standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB00837
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
ACE inhibitors Antioxidant iDPPIV
Cardiometabolic peptides Functional / health-promoting peptides
FermFooDB Peptipedia AODB AoXpDb Multi-AOP iDPPIV pep-lab
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors, Antioxidant, and iDPPIV) peptide sequence curated from FermFooDB, Peptipedia, AODB, and other sources, with an available 3D structural model.
Sequence
IPIQY
Physicochemical Analysis
C31H48N6O8
ARNDCEGHLKMFSTWV
I
632.76
5.94
0
0
3
-0
-0.53
0.520
156.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1490
235.48
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
2
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
5
C31H48N6O8
632.76
5.94
-0
-0.53
0.520
632.7463
632.3522
Evidence Records 2 records
Evidence 1 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB AoXpDb FermFooDB
DFBP
Evidence 2 Activity

Activity

IC50
iDPPIV
35.20 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Nongonierma A. B., FitzGerald R. J.
Susceptibility of milk protein-derived peptides to dipeptidyl peptidase IV (DPP-IV) hydrolysis. Food Chemistry 145, 845-852, 2014
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H]([C@H](CC)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O InChI=1S/C31H48N6O8/c1-5-17(3)25(33)30(43)37-15-7-8-23(37)28(41)36-26(18(4)6-2)29(42)34-21(13-14-24(32)39)27(40)35-22(31(44)45)16-19-9-11-20(38)12-10-19/h9-12,17-18,21-23,25-26,38H,5-8,13-16,33H2,1-4H3,(H2,32,39)(H,34,42)(H,35,40)(H,36,41)(H,44,45)/t17-,18-,21-,22-,23-,25-,26-/m0/s1 InChIKey=OPQWYASDQPRQGD-DSZQHYJTSA-N Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides
Additional Detail Fields 1 fields
5