Back to search

Peptide record

TPDB00833

ACE inhibitor ACE inhibitors Antioxidant Neuropeptide standard
5 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB00833
ACE inhibitor
ACE inhibitors Antioxidant Neuropeptide
Cardiometabolic peptides Neuroactive peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB AoXpDb Multi-AOP
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors, Antioxidant, and Neuropeptide) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
IPAGV
Physicochemical Analysis
C21H37N5O6
RNDCEQHLKMFSTWY
AGIPV
455.55
6.02
0
0
3
-0
0.05
1.700
156.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
5
C21H37N5O6
455.55
6.02
-0
0.05
1.700
455.5469
455.2735
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
93.00 µM
Inhibitor of angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Girgih AT, He R, Aluko RE.
Kinetics and molecular docking studies of the inhibitions of angiotensin converting enzyme and renin activities by hemp seed (Cannabis sativa L.) peptides. J. Agric. Food Chem. 62, 4135−4144, 2014
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)O InChI= 1S/C21H37N5O6/c1-6-12(4)16(22)20(30)26-9-7-8-14(26)19(29)24-13(5)18(28)23-10-15(27)25-17(11(2)3)21(31)32/h11-14,16-17H,6-10,22H2,1-5H3,(H,23,28)(H,24,29)(H,25,27)(H,31,32)/t12-,13-,14-,16-,17-/m0/s1 InChIKey: JJJGMSMNAASMBD-JBJRXJHCSA-N
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB AoXpDb
DFBP
Additional Detail Fields 1 fields
5