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Peptide record

TPDB00817

ACE inhibitor ACE inhibitors Antioxidant iDPPIV standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB00817
ACE inhibitor
ACE inhibitors Antioxidant iDPPIV
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AODB Multi-AOP iDPPIV
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors, Antioxidant, and iDPPIV) peptide sequence curated from Peptipedia, AODB, Multi-AOP, and other sources, with an available 3D structural model.
Sequence
IIAEK
Physicochemical Analysis
C26H48N6O8
RNDCQGHLMFPSTWYV
I
572.70
6.94
1
1
3
-0
2.22
0.680
176.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
2
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C26H48N6O8
572.70
6.94
-0
2.22
0.680
572.6928
572.3522
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
63.70 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
O. Power, A. Fernández, R. Norris, F.A. Riera, R.J. FitzGerald
Selective enrichment of bioactive properties during ultrafiltration of a tryptic digest of beta-lactoglobulin, J. Funct. Foods, 9 (2014), 38-47
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@](C(N[C@](C(N[C@](C(N[C@](C(N[C@](C(O)=O)(CCCCN)[H])=O)(CCC(O)=O)[H])=O)(C)[H])=O)([C@@H](C)CC)[H])=O)([C@@H](C)CC)[H] InChI=1S/C26H48N6O8/c1-6-14(3)20(28)24(37)32-21(15(4)7-2)25(38)29-16(5)22(35)30-17(11-12-19(33)34)23(36)31-18(26(39)40)10-8-9-13-27/h14-18,20-21H,6-13,27-28H2,1-5H3,(H,29,38)(H,30,35)(H,31,36)(H,32,37)(H,33,34)(H,39,40)/t14-,15-,16-,17-,18-,20-,21-/m0/s1 InChIKey: LMAFCBRBDQCUTK-HGDYXINXSA-N Hypocholesterolemic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9621) the MBPDB database
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
5