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Peptide record

TPDB00700

Antibacterial Antifungal Antioxidant Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB00700
Antibacterial Antifungal Antioxidant Toxicity
Anti-infective peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Antifungal, Antioxidant, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GWLKKIGKKIERVGQHTRGLGIAQIAANVAATAR
Physicochemical Analysis
C160H275N53O42
DCMFPSY
A
3613.27
12.16
8
1
15
+6
6.19
-0.171
103.53
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
152.22
5
Residue Composition
number
6
A
3
R
1
N
0
D
0
C
1
E
2
Q
5
G
1
H
4
I
2
L
4
K
0
M
0
F
0
P
0
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 6 R: 3 N: 1 D: 0 C: 0 E: 1 Q: 2 G: 5 H: 1 I: 4 L: 2 K: 4 M: 0 F: 0 P: 0 S: 0 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
34
C160H275N53O42
3613.27
12.16
+6
6.19
-0.171
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6-25 µg/mL

Target

A. umigates

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
pneumoniae, Gram-positive S. aureus, B. subtilis, B. cereus, fungi C. albicans, A. niger, A. umigates (MIC 6-25 ug/ml). It is more active against E. coli and P. aeruginosa. It showed 10% hemolysis at 100 ug/m
Evidence 2 Activity

Activity

MIC
Antifungal
6-25 µg/mL

Target

A. umigates

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
pneumoniae, Gram-positive S. aureus, B. subtilis, B. cereus, fungi C. albicans, A. niger, A. umigates (MIC 6-25 ug/ml). It is more active against E. coli and P. aeruginosa. It showed 10% hemolysis at 100 ug/m
Evidence 3 Activity

Activity

10% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Novel Antimicrobial Peptide Derived from the Insect Paederus dermatitis | Int J Pept Res Ther | 2013